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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRCA1
All Species:
11.82
Human Site:
T1246
Identified Species:
52
UniProt:
P38398
Number Species:
5
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P38398
NP_009225.1
1863
207721
T1246
S
Q
S
T
R
H
S
T
V
A
T
E
C
L
S
Chimpanzee
Pan troglodytes
Q9GKK8
1863
207881
T1246
S
Q
S
T
R
H
S
T
V
A
T
E
C
L
S
Rhesus Macaque
Macaca mulatta
Q6J6I9
1863
207771
T1246
S
Q
T
T
R
H
S
T
V
A
T
E
C
L
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P48754
1812
198651
E1215
A
V
T
Q
R
M
P
E
K
A
E
G
T
Q
A
Rat
Rattus norvegicus
O54952
1817
199849
S1208
P
E
L
T
R
C
S
S
V
V
T
Q
R
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989500
1749
193920
N1166
S
A
S
F
Y
V
T
N
R
K
D
T
S
A
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
93
N.A.
N.A.
55.4
56.3
N.A.
N.A.
32.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
95.9
N.A.
N.A.
69.4
70.2
N.A.
N.A.
49.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
13.3
33.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
33.3
60
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
17
0
0
0
0
0
0
0
67
0
0
0
17
17
% A
% Cys:
0
0
0
0
0
17
0
0
0
0
0
0
50
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% D
% Glu:
0
17
0
0
0
0
0
17
0
0
17
50
0
0
0
% E
% Phe:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
17
17
0
0
0
0
0
% K
% Leu:
0
0
17
0
0
0
0
0
0
0
0
0
0
50
0
% L
% Met:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
17
0
0
0
0
0
17
0
0
0
0
0
0
0
17
% P
% Gln:
0
50
0
17
0
0
0
0
0
0
0
17
0
17
0
% Q
% Arg:
0
0
0
0
84
0
0
0
17
0
0
0
17
0
0
% R
% Ser:
67
0
50
0
0
0
67
17
0
0
0
0
17
0
50
% S
% Thr:
0
0
34
67
0
0
17
50
0
0
67
17
17
0
0
% T
% Val:
0
17
0
0
0
17
0
0
67
17
0
0
0
17
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _